Transforming science into policy is a key challenge in ecology in the Anthropocene. Infectious diseases are increasingly recognized as a significant threat to many species of wildlife, and despite over a century of successful management of human diseases, there is limited advancement of ecological research to management action for wildlife infectious disease. This is in part due to relatively recent recognition of the importance of wildlife emerging infectious disease within ecosystems. Disease can drive abundant species to rarity or extinction, alter community composition, and change the functioning of whole systems. Despite the importance of disease as a threat to wildlife, translating the science of disease ecology into management action has been a significant challenge for conserving species. In this session, speakers will synthesize theoretical and empirical studies from diverse systems to address how to better manage the threat of wildlife disease. We hope the OOS will result in a framework for moving beyond the science of disease to better apply our knowledge to conserve species at risk.